Smoker, current or past-May increase risk for serious side effects. The effects may be increased because of slower removal of the medicine from the body. Liver disease, moderate-Use with caution. Kidney disease (eg, patients on dialysis), moderate or severe or Liver disease, severe-Use is not recommended in patients with these conditions.
Weakened immune system-May cause side effects to become worse. May increase risk of developing infections. Lymphopenia (blood disease)-Use with caution. Lung disease (eg, interstitial lung disease), or history of or Stomach or bowel problems (eg, blockage, diverticulitis, perforation, ulcers), history of-Use with caution. Hyperlipidemia (high cholesterol in the blood) or Make sure you tell your doctor if you have any other medical problems, especially:
The presence of other medical problems may affect the use of this medicine.
Bloated stomach and feeling sick and tired cd3 professional#
Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Using alcohol or tobacco with certain medicines may also cause interactions to occur. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.Ĭertain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.īacillus of Calmette and Guerin Vaccine, Live Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Drug InteractionsĪlthough certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. However, elderly patients are more likely to have serious infections, which may require caution in patients receiving tofacitinib.
GeriatricĪppropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of tofacitinib in the elderly. Safety and efficacy have been established. Safety and efficacy have not been established.Īppropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of tofacitinib tablet and oral liquid in children 2 to 17 years of age with pcJIA. Appropriate studies have not been performed on the relationship of age to the effects of tofacitinib extended-release tablet in the pediatric population.
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